Foreign pharmaceutical plastic bottles develop new trends

The pharmaceutical and medical device industries in developed countries all place great emphasis on the development of packaging. The following new types of packaging materials, new drug bottles research and development and production, is expected to completely change the traditional appearance of drug packaging, pharmaceutical packaging products to a new level.

Childproof pull-type lid plastic bottle

The vials are the most common drug packaging. They can store both solid drugs (such as tablets) and liquid drugs (such as potions). In the 1980s, the medicine bottles produced in various countries in the world mostly used glass as the bottle material, and the lids used the metal screw-open cover. The biggest drawback of this kind of bottle is that it is not tolerant to long-distance transportation, high breakage rate, loose closure of bottle caps, and easy to cause leakage, microbial contamination, moldy liquid inside, etc. This type of old glass bottle has been rarely used by pharmaceutical manufacturers in Western countries. Instead, it was replaced by a plastic bottle made of high-transparency polyester and a pull-top lid. These newly developed vials are not only highly transparent, but also resistant to drop, shock and biocompatibility, and some are easily opened due to the use of pull-top technology.

However, the pull-top transparent plastic bottle also has some disadvantages: it is easily opened by children and may cause accidental poisoning. To this end, some foreign companies have designed a child-resistant open-top plastic bottles. The series of plastic pull lids called "MAC Cover 19500" is now available in the United States.

Moisture-proof, anti-permeability new materials

Certain drugs and precision medical devices are susceptible to deterioration or damage in a wet environment, leading to reduced or even ineffective drug efficacy and changes in the performance of precision medical devices. The outer packaging of this type of product should be made of materials that completely shield moisture and oxygen.

Not long ago, the Alcoa flexible packaging company in Pittsburgh developed a new type of universal aluminum foil-plastic composite packaging material (COLDFORM3000). This new packaging material can be used as a direct outer packaging material for medicines, syringes, disposable contact lenses, and various precision medical devices. According to the person in charge of the company, COLDFORM3000 is a new composite material with excellent compactness that is processed by thickening 15% of aluminum foil, polyvinyl chloride (PVC), polyurethane and other high polymer films than ordinary aluminum foil. The outer packaging made of COLDFORM3000 can basically avoid the infiltration of moisture and oxygen, so it can greatly improve the shelf life of the product.

Another Alcoa company's new pharmaceutical packaging material is "Safety-pak Plus". It is understood that this new packaging material is made of 25 micron aluminum foil and 50 micron poly (p-phenylene terephthalate) (PET) film. Due to its good stiffness, Safety-pakPlus is ideally suited as an overwrap for valuable drugs that can prevent shock and insulate moisture and oxygen.

TelasHealth Packaging Materials of Pennsylvania, USA, has recently developed a new flexible, transparent medical packaging material called “Aclare”. The packaging material has a transparency similar to that of glass, and is made into a film to prevent the infiltration of moisture and oxygen. The material is made of a new type of high molecular polymer raw material (the manufacturer does not disclose its name), even though the thickness of the packaging material is up to 1 inch, the contents of the material can be clearly revealed. Researchers expect that Aclare's fully transparent pharmaceutical packaging materials will be widely used in the packaging of pharmaceutical products. Its main purpose is to make transparent trays and other packaging products for medical devices.
Multilayer extruded bottle

Certain bioengineering drugs (such as protein bioengineering drugs) that require special storage conditions have become one of the major products in the pharmaceutical market. In addition to their external packaging requirements must be resistant to external impact, falling and other conventional packaging requirements, but also need to be able to isolate the moisture and oxygen infiltration. US SABIC Innovative Plastics (formerly a plastics company of General Electric Company of the United States) announced not long ago that the company has developed a new type of multilayer extruded plastic bottle. It consists of 3 layers of different plastic materials: the outermost layer is a nylon material (good impact resistance); the middle layer is a polyetherimide (PEI) material; the innermost layer is a novel high-molecular polymer polycarbonate ( PC) material, which has excellent biocompatibility, is suitable for direct packaging of various products such as foods, medicines and so on. This new multi-layer extruded bottle has a very high degree of transparency and good sealability, and it can block moisture and oxygen. It can be used not only as a direct packaging for conventional blood products such as human serum albumin and fibrin collagen, but also as a packaging material for various bio-engineering drugs such as interferon and various monoclonal antibody drugs. The vial is made of the same material and is easy to use for doctors and nurses.

Intelligent voice-activated flow bottle

According to another report, Weatherchem Corporation in Ohio, USA developed a new type of capping vial. It can accurately control the amount of liquid poured out, and make the drug droplets emit a clear and audible click when poured out. The old man only had to use his thumb to hold the cap while taking the medicine, dump the bottle, and the bottle of Chinese medicine could be discharged linearly. As long as they count the corresponding clicks as instructed on the instruction manual, they can know how many doses of drug solution are flowing out, which can effectively prevent overdose. Experts anticipate that such vials with intelligent sound-control liquid outflow indicator devices will be welcomed by the manufacturer of the preparation, and the market prospect is very broad.

Anti-counterfeit bottles

Alcan Pharmaceuticals Packaging Materials of the United States has developed a new plastic bottle with an implantable electronic ID card (RFID) code. As long as you use a special scanner to scan it, you can get all the relevant product information, such as the manufacturer, production date, product lot number, product name and so on. The bottle body of this medicine bottle was embedded in the wireless scanning chip in advance and can be used for the packaging of various medical products. Its greatest advantage is that it is difficult to be imitated.

In addition, the U.S. National Association for Automatic Identification and Mobility recently announced that the association has invented a new type of bar code that can replace the bar codes that are now widely used. This set of dot codes is composed of regular patterns of several black dots on a white background. The dot code can provide up to 400 letters of information, so theoretically it can greatly exceed the product information contained in existing bar codes. The U.S. Medical Device Manufacturers Association plans to use dot codes for the packaging of medical device products.

More medical plastic bottles, please pay attention to --- plastic bottle plastic channels

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