The filling method of pharmaceutical products is basically similar to other products such as food and beverages. However, due to the high safety requirements of drugs, sterility and cleanliness must be considered when filling.
The main concern in the pharmaceutical and cosmetics industry is to focus on purity and capacity. KUGLER introduced the Variofill automatic oral liquid filling device, which is suitable for an integrated automatic production line and can also be used as an independently operated machine in pharmaceutical and cosmetics factories. The elliptical conveyor belt can handle different objects flexibly, such as round and shaped bottles, syringes and other containers made of glass or plastic. The equipment produced according to GMP (Good Manufacturing Practice) requirements is easy to operate. And can handle a variety of standard seals and special seals. Each station can be continuously adjusted to suit bottles of different heights. Quick part replacement and socket connection with virtually no tools.
The machine is compact, has a small footprint, and has a variety of standard solutions under the concept of standardization. The maximum efficiency can be achieved with only a few independent adjustments and disassembly of the pump. The open structure ensures satisfactory laminar hood acceptability, and no need to use socket-type parts for replacement, easy access and cleanliness.
For example, the company’s sales line to Shenzhen Taiwei’s liquid medicine is used to fill “Chinese medicine oral liquid†(10 ml of oral liquid and 15 ml of meditation oral liquid), and the product is poured into PP bottles and then covered with a bottom. (by hot air heat sealing), the equipment has the following production stations: feeding through the feeding plate with lifting device; through the separating worm with push-in device (the feeding worm is controlled via the servo motor), The container is transported to the conveyor system; the pressure sensor is used to control the leakage of the product; the filling station with 4 non-welding rotary piston pumps; the filling range is 2-20 ml; with a leakage under the filling nozzle Liquid tank. In order to avoid wrong filling, the pump can be closed separately; the buffer tank can hold 50 liters of liquid, including lid and liquid level switch. The reservoir includes a filter and a quick drain connector with a slow stirring device to prevent the liquid from settling.
In addition, there are four head plastic cap insertion stations, including a hot air sealing system for the external heating of containers and caps. Each heat seal head has a separate electric heating device, temperature sensor and blower. Feeding of the lid through a vibratory feeder tray; 4 heads of the coding station to distinguish each product; incorrectly produced container rejects. The rejected container will enter the closed slot at the front of the machine to prevent contamination of the machine; the product will discharge to the discharge worm on the blanking conveyor belt by 180° rotation; the container is transferred to the machine L section To carry out the process of loading a sterilized disc.
Bosch has recently developed the FLC system for the vial liquid filling machine, which operates in continuous motion and injects liquid into injection and infusion bottles. The output can be as high as more than 300 bottles per minute, and the filling volume can be as high as 500 ml. FLC Series Filling Machine Covers the most important liquid filling parts in the pharmaceutical industry.
The new filling and sealing machine is easy to operate and safe. The industrial PC can record the production data. Only by entering a few commands on the touch screen, the operator can easily perform the same production process and ensure the operating height. Safe and reliable. The conveyor system is controlled by a prism, so it can be applied to various sizes of vials.
The Ministry of equipment installed a newly developed feed turret to meet the high requirements of the pharmaceutical industry for aseptic production. Via the feed wheel, the vial is transported from the turret to the delivery system. The machine also has an option that allows the user to select the device to check the weight system so that the filling capacity can be monitored during production. If there is any deviation, the device can make adjustments automatically.
FLC's filling station is equipped with a piston pump. It can also use time pressure method or other filling system to complete the work. The system can also be equipped with "in-place cleaning" and "in-place disinfection" systems so that parts of the filling station do not need to be disassembled for cleaning and disinfection processes.
The small size of the stoppering station allows for a short distance from the plug to the completion of plugging, which minimizes the risk of particulate contamination.